Its a sympathomimetic. I have a bad cold and had to get the "real" Sudafed to help with my sinuses and my symptoms. There are many instances online of folks with ADHD self-medicating with pseudoephedrine, generally when they've run out of their script meds and are away from home or about to travel, so need a short term solution before they can get another script. I understand that people who are on adderall or ritalin can take it daily for a long period without breaks, but I also know at least anecdotally that this does cause tolerance and withdrawal issues, and that a lot of people have to increase their dosage over time on doctor's orders because of this. This issue was dealt with thoroughly in an episode of Glee about two weeks ago (episode 6, I believe). I know it works for me and it does absolute wonders, but every threads I've found about it talks about how it isn't sustainable as a stimulant and both a nasty plateau and subsequently a nasty withdrawal if you use it for too long. Internal hemorrhoids may also protrude outside the anus, where they appear as small, grape-lik… Iain Smith, in International Review of Neurobiology, 2015. This substance is a cough suppressant found in a number of over-the-counter medicines such as Robitussin. Pseudoephedrine is a stimulant found in over-the-counter and prescription decongestants. If we think that ephedrine isn’t great to start with, we easily realize what we have with pseudoephedrine, a lame high. Thanks for the info. Nicolas Rasmussen's “On Speed—The Many Lives of Amphetamine” (2008) is an excellent history of the drug first synthesized and discovered in California by Gordon Alles. Below we will examine the dangers, side effects and the true long term cost of common prescription stimulant ADHD drug abuse. Roy Fontenot, staff pharmacist at the Neighborhood Walmart on Highland Road, said while Adderall and other ADHD medications target certain receptors in the brain that increase concentration, pseudoephedrine targets different receptors, and the body reacts to it … If you've watched Breaking Bad you know very well that pseudoephedrine can be chemically modified to produce methamphetamine, aka crystal meth, which is why Sudafed was taken off pharmacy shelves in 2006 (1). I'm in a position now in which I'll be completely alone for most of the next four days and I have a pile of stuff I'd like to accomplish, so I'm tentatively considering going for the full 60mg / 4 times daily for at least today and tomorrow, and possibly going on into Sunday and Monday depending on how things are going. That’s an interesting question. The drug has a low risk of dependence, however, and withdrawal symptoms are unlikely to develop after stopping the drug. Indeed, millions of people use it each year without any dire consequences. over weekends or school holidays) to see whether it is still needed. this issue was dealt with thoroughly in an episode of glee about two weeks ago (episode 6, i believe). Your reply is very short and likely does not add anything to the thread. I am also ADHD and studying for Step 2 CK. Wellbutrin is not an FDA-approved ADHD medication, but rather an antidepressant sometimes used off label to treat ADHD symptoms including hyperactivity and distractibility in people with attention deficit hyperactivity disorder. Dextroamphetamine has a time to peak concentration of 60 to 160 minutes and is metabolized in the liver. It involves the use of two stimulants, amphetamine and dextroamphetamine, which work together to affect chemicals in the brain that calm hyperactivity and improve impulse control. 20. Your message may be considered spam for the following reasons: JavaScript is disabled. For a better experience, please enable JavaScript in your browser before proceeding. Tcheremissine OV, Salazar JO. I'm just wondering though, can anyone anecdotally describe how far one can push this in terms of consecutive days and frequency, before hitting any of the tolerance or rebound "walls"? Upsides. The FDA says that pseudoephedrine is safe when taken as directed. Expert … Wearing Many Hats as a Research Clinician-Scientist: Why and How, Texas A&M College of Medicine, College Station, TX, http://designer-drugs.com/pte/12.162.180.114/dcd/chemistry/birch.pseudo.html, http://www.ky3.com/news/local/42152887.html, http://online.wsj.com/article/SB125608176468997673.html, ADHD (again) but this time re: "presents way differently in women". Which isnt really the case, and wasnt the case for me. I broke down and tried it. Significantly more effective as a decongestant than phenylephrine. Breaks from treatment also help to prevent a slowdown in growth that sometimes happens when children take this medicine for a long time. I usually just manage by allowing for lots of breaks. 1 The drug is commonly found in combination medicines that contain other active ingredients like acetaminophen (Tylenol), antihistamines, decongestants (such as pseudoephedrine), or guaifenesin (an expectorant). ADHD Medication and Treatment Reviews Wellbutrin: ADHD Medication Review. Pharmacotherapy of adult attention deficit/hyperactivity disorder: review of evidence-based practices and future directions. That brings us back to pseudoephedrine, and retail pharmacists often receive questions about its use in patients with high blood pressure. Pharmacology. Over the years, there have been reports of heart attacks, strokes, disturbed heart rhythms, and other cardiovascular problems linked with use of pseudoephedrine. I'm also wondering how many days off one should take between cycles of this stuff to avoid tolerance and diminishing returns - in other words, for instance, if I do it a few days in a row this weekend would I be advised to stay away from it for the entirety of next week? Methamphetamine (MAMP) is a drug of abuse in the United States that is detected by urine drug testing (1). During treatment for ADHD, your doctor may stop your treatment every so often (e.g. Pseudoephedrine is sometimes abused, or used for non-medical purposes, because of its stimulant effects - it can give an excitable, hyperactive feeling and increase heart rate and blood pressure. That doesn't mean it's risk free. There was a time when pseudoephedrine was as regular to me as a multivitamin, and it was only after the sinus issues went away in my early twenties that I realised that my concentration, motivation and ability to actually finish a project are practically non-existent - I chalked this up to a couple of life changes and issues which hit me around then, and only very recently discovered pseudoephedrine's membership of the amphetamine class - and thus began to realise the correlation between my productive years, and the slide into ADHD once I stopped using the stuff. And when I did a google search, it appears that others have noticed this effect too (not too surprising I guess since it's a stimulant). Otherwise known as “smart drugs” in some circles, these meds are typically amphetamines or methylphenidate. In addition, there is a risk of over-stimulation when using the combination together. And I generally don't actually take any medications for my ADHD, even the ones I have. Pseudoephedrine Hcl is used to treat nasal and sinus congestion, or congestion of the tubes that drain fluid from your inner ears, called the eustachian (yoo-STAY-shun) tubes. It began with Sudafed, which contains the drug pseudoephedrine. Tablets, chewable tablets, liquid and nasal preparations of pseudoephedrine effectively treat nasal and sinus congestion; however, the sale of cold and flu products containing pseudoephedrine is limited to behind the counter because pseudoephedrine may be used for the illicit production of methamphetamine. And when I took the Sudafed this morning and sat down to study, I noticed that I my change in concentration/thinking etc was the same if not better than when I have had to take Ritalin or Concerta (actually, this has worked way better and I don't get a bad headache). The FDA defines pseudoephedrine as an OTC drug in accordance with the monograph and FDA regulations. Pseudoephedrine Hcl may also be used for purposes not listed in this medication guide. Adderall is a prescription medication used to treat attention deficit hyperactivity disorder (ADHD) and narcolepsy. I have a bad cold and had to get the "real" Sudafed to help with my sinuses and my symptoms. And then there's the fact that one of the favorite methods for making Methamphetamine is cooking it from pseudoephedrine. The latest research shows that ADD and ADHD can be helped by pumping more norepinephrine into the brain. There are two types: internal and external. Many things now make sense which didn't before. The most severe forms of ADHD often benefit from using prescription medication. I wouldn't be surprised if pseudoephedrine did have some ADHD benefit. I was being fascitious about actually taking it to study...Sorry, sometimes tone doesn't come across on posts. Now, the term ADHD includes ADD. I was desperate for relief since the head congestion was unbearable. Pseudoephedrine is just like ephedrine, but with the shitty factor in it. If any drug was going to fit with the American psyche in relation to entrepreneurship and hard work then these … Both Adderall (via its effects on norepinephrine) and pseudoephedrine can increase blood pressure as well as increase heart rate. MAMP is a highly addictive central nervous system (CNS) stimulant that produces a euphoric high followed by restlessness, agitation, dysphoria, paranoia and in extreme cases, psychosis. Reddit is a network of communities based on people's interests. There are many instances online of folks with ADHD self-medicating with pseudoephedrine, generally when they've run out of their script meds and are away from home or about to travel, so need a short term solution before they can get another script. This is why the Sudafed trick works - although, unfortunately, it's also a stimulant, so it has other side effects including a faster heart beat, and the jitters. Since I made the connection to my past productivity and my past pseudoephedrine use, I have found that self-medicating with pseudoephedrine HCL at the recommended nasal decongestant dosing schedule causes me to have some of the most productive days in living memory, but I'm also aware that many talk of pseudo as a medication with a very unpleasant crash and tolerance effect if one stays on it for too long. With that in mind, lately I've been choosing a day or two per week in which I'll go for it, and schedule things I very much want to focus on and complete for those days. Levomethamphetamine crosses the blood-brain-barrier and acts as a TAAR1 agonist, functioning as a selective norepinephrine releasing agent (with few or no effects on the release of dopamine), so it affects the central nervous system, although its effects are qualitatively distinct relative to those of dextromethamphetamine. What have people found? A lot of threads about it, people will say "there's a heavier withdrawal price to pay from pseudo than other amphetamines, go for adderall (or another stim) instead", but as pseudo is currently my only option, I'd like to know often to do it, and how long a break to take in between doing it, without either losing the effect or screwing up my already shabby baseline. Hemorrhoids are swollen veins near the anus. tl;dr, self medicating with an over-the-counter amphetamine called pseudoephedrine, which is primarily a norepinephrine reuptake inhibitor and secondarily a dopamine reuptake inhibitor, having incredible results and feel like my old, ambitious self for the first time in many years, and wondering how many days in a row one can use this as a stimulant without building a tolerance or experiencing too unpleasant a crash and withdrawal afterwards. Attention deficit hyperactivity disorder (ADHD) is a condition which occurs in childhood and adolescence, although it can last into adulthood, and even be initially diagnosed in adulthood. Your new thread title is very short, and likely is unhelpful. Your message is mostly quotes or spoilers. It is sold primarily as a cold and sinus medication due to its ability to relieve nasal congestion and sinus pressure. 2. It's going exceptionally well. Too many students are turning to Adderall and other ADHD drugs to gain an edge in the classroom. Find communities you're interested in, and become part of an online community! This exact question was asked to me by a woman while I was working in the pharmacy a few months ago. I am also ADHD and studying for Step 2 CK. David E. Mandelbaum, in Swaiman's Pediatric Neurology (Sixth Edition), 2017 Dextroamphetamine. An Adult ADHD diagnosis can be hard as many Dr's work on the basis that ADHD is something that 'goes away' in adult hood. Just thought this was an interesting SE of my cold medicine. Anecdotally, people who use pseudoephedrine often talk about there being a much higher price to pay than with other amphetamines in terms of the crash and withdrawal, possibly because of the stronger norepinephrine effect and the depletion that follows. Abuse of this drug quickly escalated in the 1980s, following the adoption by clandestine laboratories of simplified synthetic methods, making the drug inexpensive and readily available (2). Your reply has occurred very quickly after a previous reply and likely does not add anything to the thread. I definitely don't condone taking OTC meds like that for reasons other than that discussed by your doctor. It may not display this or other websites correctly. I have many symptoms of ADHD which I only came to realise in adulthood were treated - and therefore went unnoticed - during my teenage years due to recurrent sinusitis which involved very regular seasonal medicating with pseudoephedrine to treat. Important information Do not give pseudoephedrine to a child younger than 4 years old. I actually open one of the chapters in my book about Adult ADHD with an anedcote. 7.4 Amphetamine and Methamphetamine. Hence, many states' ban on selling more than a certain # pills to any one person within a specified period of time - and that's why some states have taken it off the OTC shelves and put it behind the pharmacists' counter. The amphetamine-class of ADHD medications includes Adderall (75% dextroamphetamine salts and 25% levoamphetamine salts), Dextroamphetamine, and Vyvanse (Lisdexamfetamine). The effect is incredible, and I don't want to fuck it up by either becoming immune to it through tolerance or taking it for so many consecutive days, that the days following are horrendous. You are using an out of date browser. ADHD and attention deficit disorder (ADD) used to be considered separate conditions. Would it be bad if I just took it everyday until my test next week? For those who have used pseudoephedrine (strong Norepinephrine reuptake inhibitor and weak Dopamine reuptake inhibitor) as a stimulant, how often can one take it without crashing too hard afterwards, or building a tolerance. For reasons which are very mundane and not something I'd bore the folks here with, I don't at this time want to go down the prescription meds route (essentially, my country's mental healthcare system sucks and it's an absolute nightmare to deal with). This is a very good question. Internal hemorrhoids form inside the anal canal and are often painless. You can have either type by itself, or both at the same time. I suggest you take a break from studying and fire up a hulu account. I originally supported this (lobbied my state legislator on the issue), but it just meant that all of the meth in town is now imported from Mexico... ...but less explosions and burning buildings! Some promoters say that it is a safer alternative to ephedrine. That being said, I currently have an upper respiratory infection and my friend suggested Sudafed Triple Action (with pseudoephedrine). Looking for OTC stimulants we can go for propylhexedrine, great high, just headaches, and blood pressure rising as side effects we need to beware of. However, they may cause intermittent bleeding, usually with bowel movements, and sometimes discharge mucus. I have been taking it for 3 days now and have noticed I … Consumer Reports explains why using ADHD meds … Your reply is very long and likely does not add anything to the thread. Other medications which work on the adrenergic system such as clonidine and Venlafaxine have some ADHD benefit. Like other stimulants, pseudoephedrine may cause appetite loss in some people. It would be prudent to speak to your doctor before using both medications together. I suggest you take a break from studying and fire up a Hulu account. The symptoms of ADHD include: Dextroamphetamine and amphetamine (brand name: Adderall) and dextroamphetamin… 1,3-DMAA is thought to have stimulant effects similar to decongestants such as pseudoephedrine, ephedrine, and others. So far, I usually only do it one day a week (generally Thursday) and sometimes two, and those days tend to be days in which I can work on one thing for hours at a time without once even thinking to start looking at social media, Reddit, the news, etc. Pseudoephedrine has had a controversial history in sports, as some athletes have used it as a performance-enhanci… It is very likely that it does not need any further discussion and thus bumping it serves no purpose. Across on posts exact question was asked to me by a woman i... Or school holidays ) to see whether it is sold primarily as a cold and sinus medication due its. It is a network of communities based on people 's interests, however, others! 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